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What does ursodiol treat? Ursodiol is used to dissolve certain types of gallstones, to prevent gallstones from forming in obese patients who are losing weight rapidly, and to treat a certain type of liver disease (primary biliary cirrhosis). Ursodiol is a bile acid.
Is PBC a serious disease? Primary biliary cholangitis a (PBC) is a progressive and chronic disease, but immediate treatment may delay the damage it causes. Although PBC affects each person differently, certain characteristics are common in each stage and phase of the disease's progression.
What are the four stages of PBC? Liver biopsy also helps stage PBC, which has 4 histologic stages: Stage 1: Inflammation, abnormal connective tissue, or both, confined to the portal areas. Stage 2: Inflammation, fibrosis, or both, confined to the portal and periportal areas. Stage 3: Bridging fibrosis. Stage 4: Cirrhosis.
What is UDCA used for? Because of this property, ursodeoxycholic acid is used to treat (cholesterol) gallstones non-surgically. It is also used to relieve itching in pregnancy for some women who suffer obstetric cholestasis.
Can liver cirrhosis cause sudden death? Cirrhosis is a fatal condition. Although mild cirrhosis can be associated with prolonged survival, most diseases that induce cirrhosis progress, at variable rates, to end‐stage liver failure. In all these studies, the assumption was made that deaths were wholly or predominantly due to liver failure.
Can PBC lead to liver cancer? Some types of autoimmune diseases that affect the liver can also cause cirrhosis. For example, in primary biliary cirrhosis (PBC) the bile ducts in the liver are damaged and even destroyed which can lead to cirrhosis. People with advanced PBC have a high risk of liver cancer.
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